Endocrine Abstracts

The aim of the study: To investigate the anti-proliferative effect of cabergoline (CAB) which was used in different regimes of suppressive therapy during 12 months in patients with prolactinoma (PROL).Subjects and methods: It was examined and underwent a 12 month course of treatment by selective dopamine agonist CAB 61 patients with PROL: microadenoma 42, macro&giant PROL - 19. (52 women/9 men) aged 16–66 years. The total duration of the disease...

Introduction: The role of the pineal gland and its hormone, melatonin, in the regulation of hypothalamo-adenohypophysial system activity is well known. At the same time, studies of the circadian rhythm of melatonin secretion in patients with pituitary adenomas are few in number, because the evaluation of pineal activity is not generally included in the clinical investigation of patients with pituitary tumors.Aim: The present study analyzed the circadian ...